Is hyperthermia a direct or indirect teratogen?
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چکیده
منابع مشابه
Is diabetes mellitus a teratogen or a coteratogen?
The risk of major and minor congenital malformations was compared in the offspring of diabetic (n = 2,639) and nondiabetic (n = 2,144) women who delivered at the Johns Hopkins Hospital in Baltimore, Maryland, between January 1, 1946 and December 31, 1970. In spite of ample power, there was little evidence of an increased malformation risk in offspring born prior to the onset of overt diabetes i...
متن کاملIs reserpine a human teratogen?
A single stillborn female with craniofacial, abdominal, and central nervous system malformations was exposed to reserpine during the first six weeks of gestation. Parallels between the malformations present in this infant and those induced in rats through exposure to reserpine at analogous periods of gestation suggest that reserpine may pose specific risks for malformations in some pregnancies.
متن کاملDirect or indirect iodine supplementation of infants?
Iodine is needed for thyroid hormone production and iodine suffi ciency is particularly important during pregnancy, lactation, and infancy owing to the role of thyroid hormones in brain development. A defi ciency of iodine during these life stages can result in impaired child cognition and has been associated with infant mortality. In countries with inadequate iodised salt coverage and iodine d...
متن کاملEthanol itself is a holoprosencephaly-inducing teratogen
Ethanol is a teratogen, inducing a variety of structural defects in developing humans and animals that are exposed in utero. Mechanisms of ethanol teratogenicity in specific defects are not well understood. Oxidative metabolism of ethanol by alcohol dehydrogenase or cytochrome P450 2E1 has been implicated in some of ethanol's teratogenic effects, either via production of acetaldehyde or competi...
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ژورنال
عنوان ژورنال: Teratology
سال: 1986
ISSN: 0040-3709,1096-9926
DOI: 10.1002/tera.1420330317